Search on: OLIGODEOXYRIBONUCLEOTIDE PROBES 
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Descriptor English:   Oligonucleotide Probes 
Descriptor Spanish:   sondas de oligonucleótidos 
Descriptor Portuguese:   Sondas de Oligonucleotídeos 
Synonyms English:   Oligodeoxyribonucleotide Probes
Oligoribonucleotide Probes
Probes, Oligodeoxyribonucleotide
Probes, Oligonucleotide
Probes, Oligoribonucleotide  
Tree Number:   D13.444.600.601
D27.505.259.750.600.650
D27.720.470.530.600.650
Definition English:   Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin. 
See Related English:   Nucleic Acid Hybridization
Oligonucleotide Array Sequence Analysis
 
History Note English:   89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   23787 
Unique Identifier:   D015345 

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